Description

2-Fluoro-1,3-Butadiene is a valuable fluorinated building block in advanced organic synthesis. This compound matters for its unique reactivity profile, enabling the introduction of fluorine atoms into complex molecular architectures, which is critical for modulating the physical and biological properties of target molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty materials industries for applications ranging from medicinal chemistry to polymer science.

Application

• Pharmaceutical Intermediate: Serves as a key synthon for the synthesis of fluorinated active pharmaceutical ingredients (APIs) and novel drug candidates.
• Agrochemical Synthesis: Used in the development of advanced fluorinated pesticides and herbicides, where fluorine enhances stability and bioactivity.
• Specialty Polymer Research: Acts as a monomer or co-monomer for creating fluorinated polymers with unique surface properties, chemical resistance, or optical characteristics.
• Material Science: Employed in the synthesis of fluorinated liquid crystals, organic semiconductors, and other advanced electronic materials.
• Organic Synthesis Building Block: Utilized in Diels-Alder reactions and other cycloadditions to construct complex, fluorinated carbocyclic and heterocyclic compounds.
• Chemical Research & Development: A versatile reagent for exploring new fluorination methodologies and reaction pathways in academic and industrial R&D settings.

Basic Information

Product Name	2-Fluoro-1,3-Butadiene
CAS No.	381-61-3
Molecular Formula	C4H5F
Molecular Weight	72.08 g/mol
Synonyms	2-Fluorobuta-1,3-diene; 2-Fluorobutadiene; 1,3-Butadiene, 2-fluoro-; 2-Fluoro-1,3-butadiene; 2-Fluorobuta-1,3-diene; 2-Fluoro-1,3-butadiene; 2-Fluorobutadiene; 2-Fluoro-1,3-butadiene
EINECS	206-838-4

Quality Control

Our 2-Fluoro-1,3-Butadiene is produced and handled under strict quality management protocols. Each batch undergoes rigorous analytical testing, including GC, NMR, and Karl Fischer titration, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates and ISO standards for industrial chemical manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, containers must be kept tightly sealed and under appropriate conditions to prevent pressure build-up and evaporation. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Report and comply with COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.