Description

2,2,2-Trifluoro-1,1-Bis(4-Methoxyphenyl)Ethanol is a specialized fluorinated aromatic alcohol that serves as a high-value synthetic intermediate. Its unique structure, featuring a trifluoroethanol moiety flanked by methoxyphenyl groups, makes it a critical building block for introducing specific steric and electronic properties into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and advanced materials sectors who require precise molecular architecture for developing novel active ingredients or functional polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring enhanced metabolic stability via fluorine incorporation.
• Agrochemical Synthesis: Building block for advanced pesticides and herbicides, where the trifluoromethyl group can improve lipophilicity and biological activity.
• Liquid Crystal & OLED Materials: Serves as a core unit in the development of fluorinated liquid crystals and organic light-emitting diode (OLED) materials, contributing to improved charge transport and thermal stability.
• Polymer & Resin Modifier: Used to introduce fluorinated segments into specialty polymers, enhancing properties such as chemical resistance, weatherability, and surface energy.
• Catalyst & Ligand Development: Potential precursor for chiral ligands or organocatalysts used in asymmetric synthesis, leveraging the steric bulk of the bis(aryl) group.
• Advanced Organic Synthesis: Versatile reagent for constructing complex, fluorinated organic molecules in academic and industrial R&D settings.

Basic Information

Product Name	2,2,2-Trifluoro-1,1-Bis(4-Methoxyphenyl)Ethanol
CAS No.	379-21-5
Molecular Formula	C16H15F3O3
Molecular Weight	312.29 g/mol
Synonyms	α,α-Bis(4-methoxyphenyl)-2,2,2-trifluoroethanol; 1,1-Bis(4-methoxyphenyl)-2,2,2-trifluoroethanol; 2,2,2-Trifluoro-1-(4-methoxyphenyl)-1-(4'-methoxyphenyl)ethanol; Trifluoro Bis(4-Methoxyphenyl) Ethanol; 2,2,2-Trifluoro-1,1-di(4-methoxyphenyl)ethanol; α-(Trifluoromethyl)-4,4'-dimethoxybenzhydrol; 379-21-5
EINECS	206-820-6

Quality Control

Our 2,2,2-Trifluoro-1,1-Bis(4-Methoxyphenyl)Ethanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical and advanced material applications. Certificates of Analysis (COA) detailing specific batch results are provided and can be tailored to meet client-specific requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.