Description

Fluoroiodomethane (CAS NO 373-53-5) is a versatile halogenated methane derivative, serving as a critical reagent for introducing fluoromethyl and iodomethyl groups in advanced synthetic chemistry. Its unique bifunctional nature makes it a valuable building block for constructing complex molecular architectures in pharmaceutical and agrochemical research. This compound is essential for researchers and process chemists in fine chemical synthesis, material science, and life sciences who require high-purity, reliable intermediates for their development pipelines.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of fluorinated active pharmaceutical ingredients (APIs) and novel drug candidates.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides that incorporate fluorine for enhanced biological activity and stability.
• Material Science Precursor: Acts as a monomer or modifying agent in the development of specialty polymers and fluorinated materials.
• Cross-Coupling Reactions: Serves as an electrophilic partner in palladium-catalyzed cross-coupling reactions (e.g., Negishi, Suzuki-Miyaura) to form carbon-carbon bonds.
• Radical Chemistry: A source of fluoromethyl or iodomethyl radicals for radical addition and cyclization reactions in organic synthesis.
• Labeling and Tracer Studies: Potential use in the preparation of compounds labeled with fluorine-18 or iodine-125 for positron emission tomography (PET) imaging and metabolic studies.

Basic Information

Product Name	Fluoroiodomethane
CAS No.	373-53-5
Molecular Formula	CH2FI
Molecular Weight	175.93 g/mol
Synonyms	Iodofluoromethane; Fluoromethyl iodide; Monofluoroiodomethane; (Fluoromethyl)iodide; Methyl iodide, fluoro-; Fluoromethyliodide; CH2FI; Iodomethyl fluoride
EINECS	206-762-1

Quality Control

Our Fluoroiodomethane is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including Gas Chromatography (GC) and Nuclear Magnetic Resonance (NMR) spectroscopy, to ensure identity, purity, and consistency. We provide full traceability and a Certificate of Analysis (COA) with every shipment, detailing all critical parameters. Our quality commitment ensures the material meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place, away from heat sources and incompatible materials. Due to its highly volatile and light-sensitive nature, it is recommended to store the container under an inert atmosphere (e.g., nitrogen or argon) at temperatures between 2°C and 8°C for long-term stability. Keep the container upright and securely sealed when not in use.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Density (at 20°C)	2.37 - 2.42 g/mL
Boiling Point	53 - 55 °C
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.