Description

1-Bromo-6-Fluorohexane is a versatile bifunctional alkyl halide building block, essential for introducing both bromo and fluoroalkyl functionalities in a single step. Its value lies in its role as a key intermediate for the synthesis of complex molecules in advanced research and industrial applications. This compound is primarily needed by pharmaceutical, agrochemical, and material science industries for constructing active ingredients, liquid crystals, and specialty polymers.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and stability.
• Liquid Crystal Manufacturing: Serves as a precursor for fluorinated mesogens, which are key components in display technologies.
• Polymer & Material Science: Employed to create specialty polymers, surfactants, and coatings with unique surface properties and chemical resistance.
• Organic Synthesis & Research: A valuable reagent in academic and industrial R&D for nucleophilic substitution reactions and the preparation of more complex fluorinated compounds.
• Cross-Coupling Reactions: Acts as an electrophile in palladium-catalyzed reactions (e.g., Suzuki, Heck) to form carbon-carbon bonds.

Basic Information

Product Name	1-Bromo-6-Fluorohexane
CAS No.	373-28-4
Molecular Formula	C6H12BrF
Molecular Weight	183.06 g/mol
Synonyms	6-Fluoro-1-bromohexane; 6-Fluorohexyl bromide; 1-Bromo-6-fluorohexane; Hexane, 1-bromo-6-fluoro-; 6-Fluorohexylbromide; ω-Fluorohexyl bromide; 6-Fluorobromohexane; 1-Fluoro-6-bromohexane
EINECS	206-770-5

Quality Control

Our 1-Bromo-6-Fluorohexane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place away from heat sources and incompatible materials such as strong bases and oxidizing agents. Due to its highly volatile nature, ensure containers are kept tightly sealed. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	1.28 - 1.32 g/mL
Refractive Index (n20/D)	1.445 - 1.455

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.