Description

1-Iodo-5-Fluoropentane is a versatile bifunctional alkylating agent featuring both iodo and fluoro substituents on a pentane backbone. This compound is valued for its role as a key building block in the synthesis of complex fluorinated molecules, enabling the introduction of fluorine atoms to modulate the biological activity and physicochemical properties of target compounds. It is primarily sought by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for applications in medicinal chemistry and specialty chemical manufacturing.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of fluorinated active pharmaceutical ingredients (APIs) and prodrugs.
• Agrochemical Synthesis: Used in the development of novel fluorinated pesticides and herbicides, where the fluorine atom enhances stability and bioactivity.
• Liquid Crystal & OLED Materials: Acts as a building block for fluorinated organic compounds used in electronic displays and optoelectronic devices.
• Positron Emission Tomography (PET) Tracer Development: Employed in the radiosynthesis of fluorine-18 labeled compounds for medical imaging.
• Organic Synthesis & Cross-Coupling Reactions: Functions as an alkyl halide reagent in nucleophilic substitution and metal-catalyzed coupling reactions (e.g., Suzuki, Negishi).
• Surface Modification Reagent: Used to introduce fluorinated alkyl chains onto surfaces or polymers to alter wettability and chemical resistance.

Basic Information

Product Name	1-Iodo-5-Fluoropentane
CAS No.	373-18-2
Molecular Formula	C5H10FI
Molecular Weight	216.04 g/mol
Synonyms	5-Fluoro-1-iodopentane; 5-Fluoropentyl Iodide; 1-Fluoro-5-iodopentane; Fluoropentyl Iodide; ω-Fluoro-ω'-iodopentane; Pentane, 1-fluoro-5-iodo-; 5-Fluoropentane-1-iodide; 1-Iodo-5-fluoropentane
EINECS	206-771-9

Quality Control

Our 1-Iodo-5-Fluoropentane is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and industrial use. We provide comprehensive analytical data including GC, NMR, and HPLC analysis to verify identity and purity. A Certificate of Analysis (COA) detailing all specifications is available with each shipment and upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. Due to its light-sensitive nature and reactivity with strong acids/organic solvents, containers should be kept sealed under an inert atmosphere when not in use to maximize shelf life.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.480 - 1.490
Density (g/mL at 20°C)	1.70 - 1.80

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.