Description

4-Fluorothiophenol is a versatile organosulfur compound featuring a thiol group and a fluorine substituent on the aromatic ring. This unique structure makes it a valuable building block in advanced organic synthesis, particularly for introducing fluorinated thiophenol moieties into target molecules. It is primarily used by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and materials science sectors for applications ranging from drug discovery to the development of specialty polymers and ligands.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in the synthesis of fluorinated compounds with potential therapeutic activity.
• Agrochemical Synthesis: Used in the research and production of novel pesticides and herbicides, where the fluorine atom can enhance biological activity and stability.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis, useful in asymmetric synthesis and cross-coupling reactions.
• Material Science: Employed in the synthesis of monomers and additives for advanced polymers, liquid crystals, and electronic materials.
• Chemical Research: A valuable reagent in academic and industrial R&D for exploring new fluorination methodologies and constructing complex sulfur-containing heterocycles.

Basic Information

Product Name	4-Fluorothiophenol
CAS No.	371-42-6
Molecular Formula	C6H5FS
Molecular Weight	128.17 g/mol
Synonyms	p-Fluorothiophenol; 4-Fluorobenzenethiol; 1-Fluoro-4-mercaptobenzene; 4-Fluorophenyl mercaptan; p-Fluorophenylthiol; 4-Fluoro-1-thiophenol; 4-Fluorothiophenol; FPhSH
EINECS	206-739-5

Quality Control

Our 4-Fluorothiophenol is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including GC and HPLC, to monitor critical parameters. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C) under an inert atmosphere (e.g., nitrogen) to minimize oxidation. Keep away from strong oxidizing agents, strong bases, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.