Description

1-Bromo-4-Iodo-2-(Trifluoromethyl)Benzene is a high-value, multi-halogenated aromatic building block essential for advanced organic synthesis. Its unique structure, featuring bromine, iodine, and a trifluoromethyl group on a benzene ring, makes it a versatile precursor for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for introducing halogenated aryl motifs and facilitating further cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides where the trifluoromethyl and halogen groups enhance biological activity and stability.
• Material Science Precursor: Serves as a building block for organic electronic materials, such as ligands for catalysts, monomers for specialty polymers, and components in organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: The bromine and iodine substituents offer orthogonal reactivity, making it an excellent substrate for sequential Suzuki, Stille, and Sonogashira couplings to build complex biaryl and conjugated systems.
• Ligand and Catalyst Development: Employed in the synthesis of sophisticated ligands for transition metal catalysis, leveraging the steric and electronic influence of the substituents.
• Fluorine Chemistry Research: A valuable compound for studying the effects of the trifluoromethyl group in medicinal and materials chemistry.

Basic Information

Product Name	1-Bromo-4-Iodo-2-(Trifluoromethyl)Benzene
CAS No.	364-11-4
Molecular Formula	C7H3BrF3I
Molecular Weight	350.90 g/mol
Synonyms	2-Bromo-5-Iodobenzotrifluoride; 4-Bromo-1-Iodo-2-(Trifluoromethyl)Benzene; 1-Bromo-4-Iodo-α,α,α-Trifluoro-o-Xylene; 2-Trifluoromethyl-1-Bromo-4-Iodobenzene; Benzene, 1-bromo-4-iodo-2-(trifluoromethyl)-; 5-Iodo-2-bromobenzotrifluoride; o-(Trifluoromethyl)-1-bromo-4-iodobenzene; 364-11-4
EINECS	Contact for details

Quality Control

Our 1-Bromo-4-Iodo-2-(Trifluoromethyl)Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures consistency and reliability for your critical research and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.