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1-Bromo-1,2-Difluoroethylene CAS NO 358-99-6


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CAS No.:358-99-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1-Bromo-1,2-Difluoroethylene is a versatile halogenated olefin building block, valued for its unique reactivity profile. This compound serves as a critical intermediate in the synthesis of complex fluorinated molecules, enabling the introduction of both bromine and fluorine atoms in a single step. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel active ingredients and specialty polymers.

Application

  • Pharmaceutical Intermediate: Used in the synthesis of fluorinated drug candidates, particularly in medicinal chemistry for lead optimization and structure-activity relationship (SAR) studies.
  • Agrochemical Synthesis: Serves as a key precursor for developing novel fluorinated pesticides and herbicides, where fluorine atoms enhance biological activity and environmental stability.
  • Fluoropolymer Modification: Acts as a monomer or comonomer in the production of specialized fluoropolymers with tailored surface properties and chemical resistance.
  • Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Heck) and nucleophilic substitution reactions to construct complex organic frameworks.
  • Liquid Crystal & Electronic Materials: Utilized in the development of fluorinated liquid crystals and dielectric materials for display and semiconductor applications.
  • Refrigerant & Propellant Research: Investigated as a potential component in next-generation, low-global-warming-potential (GWP) refrigerant blends.

Basic Information

Product Name 1-Bromo-1,2-Difluoroethylene
CAS No. 358-99-6
Molecular Formula C2HBrF2
Molecular Weight 142.93 g/mol
Synonyms 1,2-Difluoro-1-bromoethene; Bromodifluoroethylene; 1-Bromo-1,2-difluoroethene; Vinyl bromide, 1,2-difluoro-; (E)-1-Bromo-1,2-difluoroethylene; (Z)-1-Bromo-1,2-difluoroethylene; 1-Bromo-1,2-difluoroethylene (mixed isomers)
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Quality Control

Our 1-Bromo-1,2-Difluoroethylene is produced and handled under strict quality management protocols. Each batch undergoes rigorous analytical testing, including GC, GC-MS, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request, providing full traceability and compliance support for your regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, keep containers tightly sealed when not in use. Recommended storage temperature is 2-8°C for extended stability.

Specification

Item Specification
Appearance Colorless to pale yellow liquid
Identification (IR) Conforms to structure
Purity (GC) ≥ 97.0% (Isomer mixture)
Water Content (KF) ≤ 0.1%
Non-volatile Residue ≤ 0.05%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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