Description

Diethyl Fluoridophosphate is a specialized organophosphorus compound with the CAS number 358-74-7, serving as a critical intermediate in advanced chemical synthesis. Its primary value lies in its role as a key building block for the production of pharmaceuticals, agrochemicals, and flame retardants. This high-purity reagent is essential for research and manufacturing facilities in the fine chemical, life sciences, and material science industries that require precise and reliable fluorinated phosphorus reagents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those with phosphate ester or nerve agent antidote profiles.
• Agrochemical Synthesis: Used in the manufacture of advanced insecticides, herbicides, and plant growth regulators where a fluoridophosphate moiety is required.
• Chemical Research Reagent: Employed in organic and medicinal chemistry laboratories for the introduction of the diethyl fluoridophosphate group into target molecules.
• Flame Retardant Production: Acts as an intermediate in the synthesis of specialized, halogenated organophosphorus flame retardants for polymers and textiles.
• Ligand and Catalyst Preparation: Useful for modifying metal complexes and creating novel ligands in coordination chemistry and catalysis research.

Basic Information

Product Name	Diethyl Fluoridophosphate
CAS No.	358-74-7
Molecular Formula	C4H10FO3P
Molecular Weight	156.10 g/mol
Synonyms	Diethyl Fluorophosphate; Diethyl Phosphorofluoridate; Fluorophosphoric Acid Diethyl Ester; DEFP; Diethoxyphosphoryl Fluoride; Ethyl Fluorophosphate; O,O-Diethyl Fluorophosphate
EINECS	Contact for details

Quality Control

Our Diethyl Fluoridophosphate is manufactured under stringent quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including assay by NMR or titration, identity confirmation by FT-IR, and impurity profiling by GC or HPLC. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Assay (GC or NMR)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Impurities (GC)	≤ 2.0% total
Density (at 20°C)	~1.15 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.