Description

Phetharbital CAS NO 357-67-5 is a synthetic barbiturate derivative, a class of compounds historically significant in medicinal chemistry for their central nervous system depressant effects. Its precise chemical structure makes it a valuable reference standard and a key intermediate in pharmaceutical research and development. This compound is primarily utilized by research institutions, analytical laboratories, and pharmaceutical companies engaged in method development, quality control, and the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of barbiturate-related compounds in research and quality control laboratories.
• Chemical Intermediate: Serves as a crucial building block in the synthesis of more complex barbiturate derivatives and related pharmacologically active molecules.
• Neuroscience Research: Employed in preclinical studies to investigate the structure-activity relationships (SAR) of barbiturates and their effects on GABA receptors.
• Analytical Method Development: Acts as a known compound for developing and validating chromatographic (HPLC, GC) and spectroscopic analytical methods.
• Forensic Analysis: Used as a calibration standard in forensic toxicology for the detection and quantification of barbiturates.
• Academic Research & Teaching: Provides a practical example of barbiturate chemistry for educational purposes in university chemistry and pharmacology departments.

Basic Information

Product Name	Phetharbital
CAS No.	357-67-5
Molecular Formula	C12H14N2O3
Molecular Weight	234.25 g/mol
Synonyms	5,5-Diethyl-1-phenylbarbituric Acid; 1-Phenyl-5,5-diethylbarbituric Acid; NSC 30688; Phenylbarbital; Phenylethylbarbituric Acid; Phenyl-diethyl-malonylurea; Phetharbitalum
EINECS	Contact for details

Quality Control

Our Phetharbital is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical testing, including identity confirmation by IR spectroscopy and purity determination by HPLC. A detailed Certificate of Analysis (COA) specifying the exact results for assay, related substances, and residual solvents is provided with every shipment to support your research integrity and regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to prevent any potential moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.