Description

10,11-Dimethoxystrychnine is a high-purity, structurally modified alkaloid derivative of strychnine, identified by CAS NO 357-57-3. This compound is of significant value as a critical reference standard and research chemical in advanced analytical and pharmacological studies. It is primarily required by pharmaceutical R&D laboratories, academic institutions, and analytical testing facilities for method development and validation.

Application

• Pharmaceutical Reference Standard: Used as a certified standard for the identification, purity assessment, and quantification of strychnine-related alkaloids in drug substances and finished products.
• Biochemical Research: Serves as a key intermediate or probe in neuroscience and toxicology research to study the modulation of glycine receptors and other neurological pathways.
• Analytical Method Development: Essential for developing and validating high-performance liquid chromatography (HPLC), liquid chromatography-mass spectrometry (LC-MS), and other chromatographic methods in quality control labs.
• Forensic Analysis: Employed as a calibration standard in forensic toxicology for the accurate detection and measurement of strychnine and its analogs in biological samples.
• Chemical Synthesis: Acts as a sophisticated building block or precursor for the synthesis of novel compounds in medicinal chemistry programs.

Basic Information

Product Name	10,11-Dimethoxystrychnine
CAS No.	357-57-3
Molecular Formula	C23H26N2O4
Molecular Weight	394.47 g/mol
Synonyms	Strychnine, 10,11-dimethoxy-; 10,11-Dimethoxystrychnidine; 2,3-Dimethoxystrychnine; NSC 3345; 10,11-Dimethoxy-strychnidin-10-ium; Brucine dimethyl ether derivative
EINECS	Contact for details

Quality Control

Our 10,11-Dimethoxystrychnine is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (IR, NMR, MS), to ensure it meets the exacting standards required for research and analytical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and conformity to specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.