Description

2-(1,2-Dichloro-1,2,2-trifluoroethyl)thiophene is a specialized fluorinated and chlorinated heterocyclic building block. This compound is valued for its unique molecular structure, which combines a thiophene ring with a polyhalogenated ethyl side chain, making it a versatile intermediate in advanced synthetic chemistry. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical sectors for constructing complex molecules, particularly in the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, especially those requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the introduction of fluorine and chlorine atoms can significantly alter biological activity and environmental persistence.
• Material Science Research: Serves as a precursor for developing specialty polymers, liquid crystals, or organic electronic materials due to the electron-rich thiophene and halogenated components.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, nucleophilic substitutions, and other transformations to introduce complex, functionalized thiophene units into target molecules.

Basic Information

Product Name	2-(1,2-Dichloro-1,2,2-trifluoroethyl)thiophene
CAS No.	357-40-4
Molecular Formula	C6H3Cl2F3S
Molecular Weight	235.05 g/mol
Synonyms	1,2-Dichloro-1,2,2-trifluoroethyl thiophene; 2-(1,2-Dichloro-1,2,2-trifluoroethyl)-thiophene; Thiophene, 2-(1,2-dichloro-1,2,2-trifluoroethyl)-; α,β-Dichloro-α,β,β-trifluoroethyl thiophene; 2-(Dichlorotrifluoroethyl)thiophene
EINECS	Contact for details

Quality Control

Our 2-(1,2-Dichloro-1,2,2-trifluoroethyl)thiophene is produced under controlled conditions to ensure batch-to-batch consistency and high purity. Quality is verified through a suite of analytical techniques including GC, HPLC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area. Recommended storage temperature is between 2°C and 8°C for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.