Description

2-Iodo-1,1,1-Trifluoroethane is a versatile fluorinated organic building block characterized by its trifluoromethyl and iodo functional groups. This compound is valued for its ability to introduce the trifluoromethyl moiety into target molecules, a key modification in medicinal chemistry and agrochemical development. It is primarily utilized by R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors for synthesis and process optimization.

Application

• Pharmaceutical Intermediate: A key reagent for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drugs to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the trifluoromethyl group improves biological activity and environmental persistence.
• Organic Synthesis Building Block: Employed in nucleophilic substitution and cross-coupling reactions to construct complex fluorinated molecules in academic and industrial research.
• Material Science: Serves as a precursor for specialty polymers and liquid crystals where fluorine incorporation modifies surface properties and thermal stability.
• Refrigerant & Propellant Research: Investigated in the development of next-generation fluorocarbon-based refrigerants and propellants.

Basic Information

Product Name	2-Iodo-1,1,1-Trifluoroethane
CAS No.	353-83-3
Molecular Formula	C2H2F3I
Molecular Weight	209.94 g/mol
Synonyms	1,1,1-Trifluoro-2-iodoethane; Trifluoroiodoethane; Iodotrifluoroethane; 2-Iodotrifluoroethane; CF3CH2I; Ethane, 2-iodo-1,1,1-trifluoro-; 1-Iodo-2,2,2-trifluoroethane; α-Iodotrifluoroethane
EINECS	206-537-6

Quality Control

Our 2-Iodo-1,1,1-Trifluoroethane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of industrial and research applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use. Recommended storage temperature is 2-8°C for extended stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~2.0 g/mL
Boiling Point	~65-67°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.