Description

2-(4-Fluorophenyl)-5-Nitrobenzimidazole, 95% is a high-purity benzimidazole derivative, a versatile heterocyclic building block critical for advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and functional materials, where its specific fluorinated nitro-substituted structure enables precise molecular design. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with targeted biological or physical properties. The CAS number for this product is 348-35-6.

Application

This benzimidazole derivative serves as a foundational intermediate in several high-value industrial and research applications:

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting specific enzyme pathways where the benzimidazole core is pharmacologically active.
• Agrochemical Research: Used in developing new fungicides and herbicides, leveraging its heterocyclic structure for bioactivity.
• Material Science: Acts as a building block for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in charge-transport layers.
• Dye & Pigment Synthesis: Employed in the production of specialized dyes and pigments due to the nitro and fluorophenyl groups which influence color and stability.
• Academic & Contract Research: A valuable reagent for methodological development and discovery chemistry in university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	2-(4-Fluorophenyl)-5-Nitrobenzimidazole, 95%
CAS No.	348-35-6
Molecular Formula	C₁₃H₈FN₃O₂
Molecular Weight	257.22 g/mol
Synonyms	5-Nitro-2-(4-fluorophenyl)-1H-benzimidazole; 2-(p-Fluorophenyl)-5-nitrobenzimidazole; 1H-Benzimidazole, 2-(4-fluorophenyl)-5-nitro-; 348-35-6; 2-(4-Fluorophenyl)-5-nitro-1H-benzimidazole; 5-Nitro-2-(4'-fluorophenyl)benzimidazole
EINECS	Contact for details

Quality Control

Our 2-(4-Fluorophenyl)-5-Nitrobenzimidazole, 95% is produced and tested under a rigorous quality management system. Each batch is analyzed to confirm identity, purity, and impurity profile, ensuring consistency for research and development applications. A comprehensive Certificate of Analysis (COA) detailing the results of HPLC assay, related substances, and other relevant tests is provided with every shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.