Description

S-(4-Fluorophenyl)-L-Cysteine is a fluorinated derivative of the amino acid L-cysteine, featuring a 4-fluorophenyl group attached to the sulfur atom. This specific structural modification makes it a valuable chiral building block and intermediate in advanced organic synthesis, particularly for introducing fluorine-containing motifs into target molecules. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for the development of novel active compounds and biochemical probes.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of fluorinated drug candidates, including protease inhibitors and enzyme modulators.
• Biochemical Research: Used in proteomics and enzymology studies to investigate protein structure-function relationships and enzyme mechanisms involving cysteine residues.
• Agrochemical Synthesis: Serves as a building block for creating novel fluorinated pesticides and herbicides with potentially enhanced activity and selectivity.
• Peptide Chemistry: Incorporated into custom peptides to study the effects of fluorinated aromatic groups on peptide stability, bioavailability, and receptor binding.
• Ligand and Catalyst Development: Utilized in the synthesis of chiral ligands for asymmetric catalysis and metal-chelating agents.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	S-(4-Fluorophenyl)-L-Cysteine
CAS No.	331-90-8
Molecular Formula	C9H10FNO2S
Molecular Weight	215.25 g/mol
Synonyms	L-Cysteine, S-(4-fluorophenyl)-; (R)-2-Amino-3-((4-fluorophenyl)thio)propanoic acid; 4-Fluorophenyl-L-cysteine; S-(p-Fluorophenyl)-L-cysteine; (2R)-2-Amino-3-[(4-fluorophenyl)sulfanyl]propanoic acid; FPHC; 331-90-8; S-4-Fluorophenylcysteine
EINECS	Contact for details

Quality Control

Our S-(4-Fluorophenyl)-L-Cysteine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, confirming identity, purity, and specification compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.