Description

5-Nitro-2-Trifluoromethylbenzimidazole is a high-value, multi-functional heterocyclic building block characterized by its nitro and trifluoromethyl substituents. This compound is essential for researchers and manufacturers requiring precise molecular modifications to develop advanced materials and active pharmaceutical ingredients. It is primarily utilized in the agrochemical, pharmaceutical, and specialty chemical sectors for applications ranging from synthesis intermediates to functional material precursors.

Application

• Pharmaceutical Intermediate: A key synthon in the development of novel benzimidazole-based drug candidates, particularly those targeting infectious diseases and oncology.
• Agrochemical Synthesis: Serves as a critical precursor for creating next-generation fungicides, herbicides, and pesticides with enhanced efficacy and environmental profiles.
• Organic Light-Emitting Diodes (OLEDs): Used in the research and development of electron-transport materials and emissive layers due to its electron-deficient aromatic system.
• Coordination Chemistry & Ligand Design: Acts as a versatile ligand or precursor for metal-organic frameworks (MOFs) and catalytic complexes.
• Dye & Pigment Industry: Employed in the synthesis of specialized dyes and pigments where the nitro and trifluoromethyl groups impart specific color and stability properties.
• Material Science Research: Investigated for use in polymers and advanced organic semiconductors to modify electronic properties.

Basic Information

Product Name	5-Nitro-2-Trifluoromethylbenzimidazole
CAS No.	327-19-5
Molecular Formula	C8H4F3N3O2
Molecular Weight	231.13 g/mol
Synonyms	2-(Trifluoromethyl)-5-nitro-1H-benzimidazole; 5-Nitro-2-(trifluoromethyl)-1H-benzimidazole; 1H-Benzimidazole, 5-nitro-2-(trifluoromethyl)-; 5-Nitro-2-trifluoromethyl-1H-benzimidazole; 327-19-5; NTB; NTFB
EINECS	Contact for details

Quality Control

Our 5-Nitro-2-Trifluoromethylbenzimidazole is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) for all shipments, supporting compliance with cGMP and ISO 9001 standards for research and industrial use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, handling should be conducted under appropriate conditions to maintain product integrity.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.