Description

1-(5-Chloro-Thiophen-2-Yl)-4,4,4-Trifluoro-Butane-1,3-Dione is a high-purity, specialized organic building block featuring a unique trifluoromethylated β-diketone structure. This compound is valued for its role as a key synthetic intermediate in the development of advanced materials and active pharmaceutical ingredients (APIs). It is primarily sought by research and development teams and production chemists in the pharmaceutical, agrochemical, and advanced material science sectors.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Acts as a versatile chelating agent for the preparation of metal-organic complexes and catalysts used in asymmetric synthesis.
• Advanced Material Research: Employed in the synthesis of organic semiconductors, liquid crystals, and polymers with tailored electronic and optical properties.
• Fluorine Chemistry Building Block: Provides a source of the CF3 group for introducing fluorine atoms into target molecules, a common strategy in modern medicinal chemistry.

Basic Information

Product Name	1-(5-Chloro-Thiophen-2-Yl)-4,4,4-Trifluoro-Butane-1,3-Dione
CAS No.	326-73-8
Molecular Formula	C8H4ClF3O2S
Molecular Weight	256.63 g/mol
Synonyms	5'-Chloro-2'-thenoyltrifluoroacetone; 1-(5-Chloro-2-thienyl)-4,4,4-trifluoro-1,3-butanedione; 4,4,4-Trifluoro-1-(5-chloro-2-thienyl)-1,3-butanedione; CTTA; 5-Chloro-2-thenoyltrifluoroacetone; 1-(5-Chloro-2-thienyl)-4,4,4-trifluorobutane-1,3-dione; TTA derivative
EINECS	Contact for details

Quality Control

Our 1-(5-Chloro-Thiophen-2-Yl)-4,4,4-Trifluoro-Butane-1,3-Dione is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.