Description

4-(5-Fluoro-1H-Indol-3-Yl)-Butyric Acid is a high-purity fluorinated indole derivative, serving as a critical advanced pharmaceutical intermediate. Its value lies in its role as a versatile building block for synthesizing complex bioactive molecules, particularly in medicinal chemistry. This compound is essential for research and development laboratories, pharmaceutical manufacturers, and fine chemical producers focused on creating novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities in drug discovery programs.
• Biochemical Reagent: Employed in biochemical research to study enzyme interactions and receptor binding activities due to its indole-based structure.
• Fine Chemical Synthesis: Serves as a specialized building block for the production of complex fluorinated organic compounds in custom synthesis projects.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	4-(5-Fluoro-1H-Indol-3-Yl)-Butyric Acid
CAS No.	319-72-2
Molecular Formula	C₁₂H₁₂FNO₂
Molecular Weight	221.23 g/mol
Synonyms	5-Fluoro-3-indolebutyric acid; 4-(5-Fluoro-1H-indol-3-yl)butanoic acid; 5-Fluoroindole-3-butyric acid; γ-(5-Fluoro-3-indolyl)butyric acid; 5-Fluoro-IBA; 5-F-IBA; 4-(5-Fluoro-1H-indol-3-yl)butyric acid; (5-Fluoro-1H-indol-3-yl)-butanoic acid
EINECS	Contact for details

Quality Control

Our 4-(5-Fluoro-1H-Indol-3-Yl)-Butyric Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider using a desiccant in the storage environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.