Description

Trimethyl(2,2,3,3-Tetrafluorocyclobutyl)Silane is a specialized organosilicon compound featuring a unique tetrafluorocyclobutyl group. This structure makes it a valuable synthetic intermediate and building block for introducing fluorinated moieties into target molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and advanced materials sectors for creating novel compounds with tailored properties.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of fluorinated active pharmaceutical ingredients (APIs) and drug candidates, leveraging the metabolic stability and lipophilicity imparted by fluorine.
• Agrochemical Synthesis: Used in the development of next-generation fluorinated pesticides and herbicides, where the fluorine atoms can enhance biological activity and environmental persistence.
• Advanced Material Precursor: Acts as a monomer or modifying agent in the production of specialty polymers, coatings, and silicones with enhanced chemical resistance, low surface energy, or specific optical properties.
• Liquid Crystal & OLED Materials: Employed in the synthesis of fluorinated components for electronic displays and organic light-emitting diodes (OLEDs) to improve performance and stability.
• Surface Modification Agent: Utilized to create hydrophobic, oleophobic, or release surfaces on glass, metals, and polymers via silane chemistry.
• Cross-Coupling Reagent: Functions as an organosilicon reagent in Hiyama-type cross-coupling reactions for carbon-carbon bond formation in complex molecule assembly.

Basic Information

Product Name	Trimethyl(2,2,3,3-Tetrafluorocyclobutyl)Silane
CAS No.	312-81-2
Molecular Formula	C7H12F4Si
Molecular Weight	200.25 g/mol
Synonyms	(2,2,3,3-Tetrafluorocyclobutyl)trimethylsilane; Trimethyl(2,2,3,3-tetrafluorocyclobutyl)silane; Silane, trimethyl(2,2,3,3-tetrafluorocyclobutyl)-; 1-(Trimethylsilyl)-2,2,3,3-tetrafluorocyclobutane; (Tetrafluorocyclobutyl)trimethylsilane; 2,2,3,3-Tetrafluorocyclobutyltrimethylsilane
EINECS	Contact for details

Quality Control

Our Trimethyl(2,2,3,3-Tetrafluorocyclobutyl)Silane is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including GC, NMR, and HPLC analysis, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality systems are designed to support cGMP requirements for use in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~1.10 g/cm³
Refractive Index (n20D)	~1.380

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.