Description

6,7-Dihydroxycoumarin is a naturally occurring polyphenolic compound belonging to the coumarin class, also known as esculetin. This high-purity intermediate is valued for its significant biological activity and serves as a versatile building block in advanced organic synthesis. It is essential for manufacturers and research institutions in the pharmaceutical, nutraceutical, and fine chemical sectors seeking a reliable source for this key bioactive molecule.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various bioactive molecules and active pharmaceutical ingredients (APIs) targeting inflammation and oxidative stress.
• Cosmetic & Personal Care: Incorporated into formulations for its antioxidant and skin-brightening properties, often found in anti-aging and protective skincare products.
• Nutraceutical & Dietary Supplements: Used as a functional ingredient in supplements for its potential health-promoting and wellness-supporting benefits.
• Biochemical Research: Employed as a standard or reagent in life science research to study enzyme inhibition, antioxidant mechanisms, and cellular pathways.
• Fine Chemical Synthesis: Serves as a versatile scaffold for synthesizing more complex coumarin derivatives and specialty chemicals.
• Analytical Reference Standard: Supplied as a high-purity certified reference material (CRM) for quality control and analytical method development in laboratories.

Basic Information

Product Name	6,7-Dihydroxycoumarin
CAS No.	305-35-6
Molecular Formula	C9H6O4
Molecular Weight	178.14 g/mol
Synonyms	Esculetin; 6,7-Dihydroxy-2H-chromen-2-one; 6,7-Dihydroxycoumarin; Cichorigenin; Aesculetin; Esculetol; 6,7-Dihydroxy-1-benzopyran-2-one
EINECS	206-171-6

Quality Control

Our 6,7-Dihydroxycoumarin is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent specifications for high-value applications. Certificates of Analysis (COA) detailing all quality parameters are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Melting Point	268°C - 272°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.