Description

2-(2,5-Dioxopyrrolidine-3-Yl)-1H-Isoindole-1,3(2H)-Dione is a heterocyclic organic compound featuring both isoindole-1,3-dione and pyrrolidine-2,5-dione moieties, making it a versatile building block for advanced synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in pharmaceutical research and specialty polymer chemistry. It is needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries seeking to create novel active ingredients or functional polymers.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting neurological or oncological pathways.
• Polymer Chemistry: Serves as a monomer or cross-linking agent in the production of high-performance polyimides and other heat-resistant, specialty polymers.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Bioconjugation & Linker Chemistry: Its reactive dione structures make it suitable for creating cleavable linkers in antibody-drug conjugates (ADCs) and other bioconjugation applications.
• Material Science Research: Employed in developing organic electronic materials, such as semiconductors for OLEDs or photovoltaic cells.
• Chemical Biology Probes: Acts as a scaffold for designing molecular probes to study enzyme function and protein interactions.

Basic Information

Product Name	2-(2,5-Dioxopyrrolidine-3-Yl)-1H-Isoindole-1,3(2H)-Dione
CAS No.	303-16-2
Molecular Formula	C12H8N2O4
Molecular Weight	244.20 g/mol
Synonyms	3-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-2,5-dihydro-1H-pyrrole-2,5-dione; 2-(2,5-Dioxo-3-pyrrolidinyl)-1H-isoindole-1,3(2H)-dione; 3-(1,3-Dioxoisoindolin-2-yl)pyrrolidine-2,5-dione; N-(2,5-Dioxopyrrolidin-3-yl)phthalimide; 2-(2,5-Dioxo-3-pyrrolidinyl)phthalimide; 3-Phthalimidopyrrolidine-2,5-dione
EINECS	206-138-7

Quality Control

Our 2-(2,5-Dioxopyrrolidine-3-Yl)-1H-Isoindole-1,3(2H)-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.