Description

Benzo[B]Thiophene-4-Carboxylic Acid, 2-Amino-3-Cyano-4,5,6,7-Tetrahydro-4-Methyl-, (4R)- is a high-purity, chiral synthetic intermediate of significant importance in advanced pharmaceutical research and development. Its unique stereochemistry and functionalized benzo[b]thiophene core make it a valuable building block for constructing complex, biologically active molecules. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel therapeutic candidates and active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in therapeutic areas targeting the central nervous system, oncology, and metabolic diseases.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Organic Synthesis Building Block: Serves as a versatile precursor in academic and industrial organic chemistry for constructing complex polycyclic and heterocyclic frameworks.
• Material Science Research: Investigated as a potential monomer or dopant in the development of advanced organic electronic materials due to its conjugated system.
• Chemical Biology Probe Development: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	Benzo[B]Thiophene-4-Carboxylic Acid, 2-Amino-3-Cyano-4,5,6,7-Tetrahydro-4-Methyl-, (4R)-
CAS No.	2938170-12-6
Molecular Formula	C12H14N2O2S
Molecular Weight	250.32 g/mol
Synonyms	(4R)-2-Amino-3-cyano-4-methyl-4,5,6,7-tetrahydrobenzo[b]thiophene-4-carboxylic acid; (4R)-2-Amino-3-cyano-4-methyl-4,5,6,7-tetrahydro-1-benzothiophene-4-carboxylic acid; 4R-Benzo[b]thiophene-4-carboxylic acid derivative; 2-Amino-3-cyano-4-methyl-4,5,6,7-tetrahydrobenzo[b]thiophene-4-carboxylic acid (4R-isomer); ATCT; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our Benzo[B]Thiophene-4-Carboxylic Acid, 2-Amino-3-Cyano-4,5,6,7-Tetrahydro-4-Methyl-, (4R)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee (4R)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.