Description

1H-Pyrrolizine-7A(5H)-Methanol, Tetrahydro-2-Methylene-, (7As)- is a high-purity, advanced pharmaceutical intermediate characterized by its specific stereochemistry. This compound matters as a critical building block in modern organic synthesis, enabling the development of novel active pharmaceutical ingredients (APIs) with precise molecular configurations. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating complex, biologically active molecules.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of complex drug candidates, particularly in neurological and metabolic disorder research.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides where specific stereochemistry influences biological activity.
• Asymmetric Catalysis: Acts as a precursor or ligand in catalytic systems for stereoselective chemical transformations.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.
• Academic & Contract Research: A valuable reagent for university laboratories and CROs (Contract Research Organizations) exploring new synthetic methodologies.
• Process Chemistry Development: Used for scaling up and optimizing synthetic routes from laboratory to pilot plant and commercial production.

Basic Information

Product Name	1H-Pyrrolizine-7A(5H)-Methanol, Tetrahydro-2-Methylene-, (7As)-
CAS No.	2820536-99-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	(7aS)-Tetrahydro-2-methylidene-1H-pyrrolizine-7a(5H)-methanol; Tetrahydro-2-methylidene-1H-pyrrolizine-7a(5H)-methanol, (7aS)-; 1H-Pyrrolizine-7a(5H)-methanol, tetrahydro-2-methylene-, (7aS)-; 2820536-99-8; (7aS)-2-Methylideneoctahydro-1H-pyrrolizine-7a-methanol; Pyrrolizine methanol derivative
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolizine-7A(5H)-Methanol, Tetrahydro-2-Methylene-, (7As)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assay and impurity profiling, to ensure it meets the exacting standards required for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data (HPLC/GC) are provided for every shipment, guaranteeing traceability and consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). For long-term storage, consider maintaining the material under an inert atmosphere to preserve stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.