Description

1H-Indazole, 4-Bromo-6-Chloro-5-Iodo-1-(Tetrahydro-2H-Pyran-2-Yl)- is a high-value, multi-halogenated indazole derivative designed for advanced synthetic chemistry. This compound serves as a critical pharmaceutical intermediate and building block for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily utilized by research institutions and industrial R&D departments focused on medicinal chemistry, drug discovery, and material science.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly in oncology and CNS therapeutic areas.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis.
• Agrochemical Development: Serves as a building block for creating novel herbicides, fungicides, and pesticides.
• Chemical Biology Probes: Employed in the design of molecular probes for studying biological pathways and target validation.
• Material Science: Potential use in the synthesis of specialty polymers and advanced organic electronic materials.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations for custom synthesis and process development projects.

Basic Information

Product Name	1H-Indazole, 4-Bromo-6-Chloro-5-Iodo-1-(Tetrahydro-2H-Pyran-2-Yl)-
CAS No.	2791273-88-4
Molecular Formula	C12H11BrClINO
Molecular Weight	427.49 g/mol
Synonyms	4-Bromo-6-chloro-5-iodo-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole; 4-Bromo-6-chloro-5-iodo-1-(tetrahydro-2-pyranyl)-1H-indazole; 1-(Oxan-2-yl)-4-bromo-6-chloro-5-iodo-1H-indazole; 1-(Tetrahydro-2H-pyran-2-yl)-4-bromo-6-chloro-5-iodo-1H-indazole; 1H-Indazole, 4-bromo-6-chloro-5-iodo-1-(tetrahydro-2H-pyran-2-yl)-; THP-protected 4-Bromo-6-chloro-5-iodoindazole; 4-Bromo-6-chloro-5-iodo-1H-indazole THP ether
EINECS	Contact for details

Quality Control

Our high-purity intermediates are manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and LC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development and commercial projects with reliable supply and custom synthesis capabilities to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere or in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.