Description

Jwh 398 n-Pentanoic Acid Metabolite-D5 is a stable isotope-labeled internal standard, specifically a deuterated analog of a key carboxylic acid metabolite. This compound is essential for achieving high-fidelity quantitative analysis in advanced mass spectrometry, providing critical compensation for matrix effects and analyte loss during sample preparation. It is primarily required by analytical laboratories and research institutions in the fields of forensic toxicology, pharmaceutical metabolism studies, and doping control for precise and reliable quantification.

Application

• Quantitative Reference Standard in LC-MS/MS: Serves as an indispensable internal standard for the accurate quantification of the parent JWH-398 metabolite in complex biological matrices such as urine, blood, and plasma.
• Forensic Toxicology and Doping Control: Enables laboratories to perform legally defensible, high-precision analysis for the detection of synthetic cannabinoid abuse in forensic and anti-doping programs.
• Pharmacokinetic and Metabolism Research: Used in ADME (Absorption, Distribution, Metabolism, Excretion) studies to track and quantify metabolite formation and clearance rates in preclinical and clinical research.
• Method Development and Validation: Critical for developing, optimizing, and validating robust analytical methods according to guidelines from agencies like the FDA and EMA.
• Quality Control in Reference Material Production: Employed in the manufacturing and certification of certified reference materials (CRMs) to ensure batch-to-batch consistency and traceability.

Basic Information

Item	Details
Product Name	Jwh 398 n-Pentanoic Acid Metabolite-D5
CAS No.	2749394-76-9
Molecular Formula	C23H28D5NO3
Molecular Weight	Contact for details
Synonyms	JWH-398 Pentanoic Acid Metabolite-d5; 5-Deuteropentyl JWH-398 Metabolite; [D5]-JWH-398 N-Pentanoic Acid Metabolite; JWH-398 N-(5-Carboxypentyl) Metabolite-d5; Deuterated JWH-398 Carboxy Metabolite; Internal Standard for JWH-398 Acid Metabolite; JWH-398-d5 Acid Metabolite; Synthetic Cannabinoid Metabolite Reference Standard-d5
EINECS	Contact for details

Quality Control

Every batch of Jwh 398 n-Pentanoic Acid Metabolite-D5 is produced and analyzed under strict quality management protocols to ensure the high chemical purity and isotopic enrichment required for analytical applications. Our quality assurance includes comprehensive testing via NMR, HPLC, and mass spectrometry to confirm identity, purity, and deuterium incorporation. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting batch-specific data.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. Allow the sealed vial to equilibrate to room temperature before opening to prevent moisture condensation. The product should be stored in a cool, dry place dedicated for research chemicals.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC-MS)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Isotopic Purity (Deuterium Incorporation)	≥ 98 atom % D
Chemical Purity	≥ 90%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.