Description

Cinoxacin-D5 CAS NO 2732985-25-8 is a deuterated analog of the quinolone antibiotic cinoxacin, where five hydrogen atoms are replaced with the stable isotope deuterium. This compound is of critical importance as a high-purity internal standard for the precise quantification of cinoxacin in complex matrices using advanced analytical techniques like LC-MS/MS. It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and analytical testing facilities engaged in pharmacokinetic studies, metabolism research, and regulatory compliance testing.

Application

• Internal Standard for Mass Spectrometry: Essential for accurate and reliable quantification of cinoxacin in bioanalytical methods (plasma, serum, urine) using LC-MS/MS.
• Drug Metabolism and Pharmacokinetics (DMPK): Used in ADME (Absorption, Distribution, Metabolism, Excretion) studies to track and measure the parent drug and its metabolites.
• Pharmaceutical Quality Control: Serves as a reference standard in the analysis of drug substance and finished product purity and stability.
• Clinical Research: Supports therapeutic drug monitoring and bioequivalence studies in clinical trial sample analysis.
• Veterinary Drug Analysis: Applied in the detection and quantification of cinoxacin residues in food-producing animals and environmental samples.
• Forensic Toxicology: Aids in the confirmatory analysis of cinoxacin in forensic investigations.

Basic Information

Product Name	Cinoxacin-D5
CAS No.	2732985-25-8
Molecular Formula	C12H5D5N2O5
Molecular Weight	~ 267.26 g/mol
Synonyms	1-Ethyl-1,4-dihydro-4-oxo[1,3]dioxolo[4,5-g]cinnoline-3-carboxylic-5,6,7,8-d4 acid-d; Cinoxacin (ethyl-d5); Cinoxacin-d5; 1-Ethyl-1,4-dihydro-4-oxo[1,3]dioxolo[4,5-g]cinnoline-3-carboxylic acid-d5; Deuterated Cinoxacin; Cinoxacin Internal Standard
EINECS	Contact for details

Quality Control

Our Cinoxacin-D5 is manufactured under strict quality systems to ensure the highest isotopic purity and chemical integrity required for sensitive analytical applications. Each batch is characterized by advanced spectroscopic methods (NMR, MS) and undergoes rigorous purity testing via HPLC. A comprehensive Certificate of Analysis (COA) is provided, detailing isotopic enrichment (typically ≥98% D), chemical purity (≥95%), and analytical results. We support compliance with GMP/GLP guidelines for research use.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Isotopic Purity (Deuterium Enrichment)	≥ 98 atom % D
Chemical Purity (by HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.