Description

4-Isoquinolinol, 6-(Trifluoromethyl)- is a specialized trifluoromethyl-substituted isoquinoline derivative, a high-value building block in modern synthetic chemistry. Its core value lies in the unique combination of the isoquinoline scaffold and the trifluoromethyl group, which is critical for modulating the physicochemical and biological properties of target molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the discovery and synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) targets, anti-infectives, and oncology therapies.
• Agrochemical Research: Used in developing new generations of herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances lipophilicity and metabolic stability.
• Material Science: Investigated as a monomer or functional additive for creating advanced polymers and organic electronic materials with specific optical or electronic properties.
• Ligand Synthesis: Employed in the preparation of novel chelating ligands for catalysis and metal-organic frameworks (MOFs).
• Fluorine Chemistry Research: A valuable substrate for studying fluorination reactions and the effects of fluorine substitution in heterocyclic systems.

Basic Information

Item	Details
Product Name	4-Isoquinolinol, 6-(Trifluoromethyl)-
CAS No.	2708281-70-1
Molecular Formula	C10H6F3NO
Molecular Weight	213.16 g/mol
Synonyms	6-(Trifluoromethyl)isoquinolin-4-ol; 6-(Trifluoromethyl)-4-hydroxyisoquinoline; 4-Hydroxy-6-(trifluoromethyl)isoquinoline; 6-Trifluoromethyl-4-isoquinolinol; 4-Isoquinolinol, 6-(trifluoromethyl)-; 6-Trifluoromethylisoquinolin-4-ol; 6-Trifluoromethyl-4-hydroxyisoquinoline
EINECS	Contact for details

Quality Control

Our 4-Isoquinolinol, 6-(Trifluoromethyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurities, and physical data are provided with every shipment to support your R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.