Description

(S)-6-Methoxy-1,2,3,4-Tetrahydroisoquinoline-1-Carboxylic Acid Hydrochloride is a high-purity chiral building block and pharmaceutical intermediate of significant commercial interest. Its value lies in its defined stereochemistry and functional groups, which are critical for synthesizing active pharmaceutical ingredients (APIs) with specific biological activity. This compound is essential for research institutions and manufacturers in the pharmaceutical and fine chemical sectors developing novel therapeutics.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and cardiovascular targets.
• Asymmetric Synthesis: Used as a precursor or catalyst ligand in stereoselective chemical reactions to create enantiomerically pure compounds.
• Peptidomimetics & Bioactive Molecule Construction: Serves as a constrained scaffold for designing and synthesizing peptide analogs and other bioactive molecules.
• Chemical Reference Standard: Employed as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Academic & Industrial R&D: Utilized in medicinal chemistry programs for structure-activity relationship (SAR) studies and lead optimization.

Basic Information

Product Name	(S)-6-Methoxy-1,2,3,4-Tetrahydroisoquinoline-1-Carboxylic Acid Hydrochloride
CAS No.	2703746-36-3
Molecular Formula	C11H14ClNO3
Molecular Weight	243.69 g/mol
Synonyms	(1S)-6-Methoxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid hydrochloride; (S)-6-Methoxy-1,2,3,4-tetrahydro-1-isoquinolinecarboxylic acid hydrochloride; (S)-6-Methoxy-Tic-OH.HCl; (S)-1-Carboxy-6-methoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride; 6-Methoxy-(S)-Tic-OH.HCl; (S)-6-Methoxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid HCl salt
EINECS	Contact for details

Quality Control

Our (S)-6-Methoxy-1,2,3,4-Tetrahydroisoquinoline-1-Carboxylic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D and production. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and other critical specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.