Description

Bromo-3-(3-((tert-Butyldiphenylsilyl)Oxy)-2,2-Dimethylpropyl)-1H-Indole is a sophisticated, high-purity synthetic intermediate featuring a protected hydroxyl group, making it a critical building block for advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially those containing indole or protected alcohol functionalities.
• Agrochemical Research: Used in the development of new pesticides and herbicides where the indole scaffold and silyl protecting group are advantageous.
• Organic Synthesis Reagent: Serves as a versatile precursor for cross-coupling reactions, nucleophilic substitutions, and further functionalization in complex molecule assembly.
• Material Science Precursor: Potential use in the synthesis of organic semiconductors, ligands for catalysts, or advanced polymers.
• Academic & Contract Research: Essential for medicinal chemistry programs and methodological studies in university and CRO (Contract Research Organization) laboratories.

Basic Information

Item	Detail
Product Name	Bromo-3-(3-((tert-Butyldiphenylsilyl)Oxy)-2,2-Dimethylpropyl)-1H-Indole
CAS No.	2641451-59-2
Molecular Formula	C29H34BrNOSi
Molecular Weight	520.58 g/mol
Synonyms	3-Bromo-1H-indole-3-propanol, 2,2-dimethyl-, 3-(1,1-dimethylethyl)diphenylsilyl ether; 3-Bromo-1H-indole-3-propanol, 2,2-dimethyl-, 3-[(1,1-dimethylethyl)diphenylsilyl]oxy]-; 1H-Indole, 3-bromo-3-[3-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-2,2-dimethylpropyl]-; TBDPS-protected 3-bromoindole propanol derivative; 3-(3-((tert-Butyldiphenylsilyl)oxy)-2,2-dimethylpropyl)-3-bromo-1H-indole
EINECS	Contact for details

Quality Control

Our Bromo-3-(3-((tert-Butyldiphenylsilyl)Oxy)-2,2-Dimethylpropyl)-1H-Indole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP (current Good Manufacturing Practice) standards for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.