Description

tert-Butyl 4-Methyl-2-Piperazin-1-Yl-1,3-Thiazole-5-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its specific piperazine-thiazole core structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly in areas such as oncology and central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of complex drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new molecules with improved efficacy and safety profiles.
• API Development: Integral to the process development and scale-up of potential new active pharmaceutical ingredients, especially those containing heterocyclic scaffolds.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and clinical trial material production.
• Biochemical Tool Compound: May be utilized in biochemical assays to study specific biological interactions and mechanisms of action.

Basic Information

Product Name	tert-Butyl 4-Methyl-2-Piperazin-1-Yl-1,3-Thiazole-5-Carboxylate
CAS No.	2639455-19-7
Molecular Formula	C13H21N3O2S
Molecular Weight	283.39 g/mol
Synonyms	1,3-Thiazole-5-carboxylic acid, 4-methyl-2-(1-piperazinyl)-, 1,1-dimethylethyl ester; 4-Methyl-2-piperazin-1-yl-1,3-thiazole-5-carboxylic acid tert-butyl ester; tert-Butyl 4-methyl-2-(piperazin-1-yl)thiazole-5-carboxylate; 2-(Piperazin-1-yl)-4-methylthiazole-5-carboxylic acid tert-butyl ester; 2639455-19-7
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-Methyl-2-Piperazin-1-Yl-1,3-Thiazole-5-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, containers should be kept tightly sealed to minimize exposure to atmospheric humidity. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.