Description

Phospholane, 1-[2-[(2R,5R)-2,5-Diethyl-1-Oxido-1-Phospholanyl]Phenyl]-2,5-Diethyl-, (2R,5R)-Rel- CAS NO 2635339-89-6 is a high-purity, stereochemically defined organophosphorus compound. This advanced chiral ligand is critical for enabling asymmetric catalysis, particularly in the synthesis of complex pharmaceutical intermediates and fine chemicals. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors who require precise stereocontrol in their synthetic processes.

Application

• Asymmetric Catalysis: As a chiral ligand in transition metal-catalyzed reactions, including hydrogenation, hydroformylation, and cross-coupling.
• Pharmaceutical Intermediate Synthesis: For the enantioselective production of active pharmaceutical ingredients (APIs) and key chiral building blocks.
• Agrochemical Development: In the synthesis of chiral pesticides, herbicides, and plant growth regulators.
• Fine Chemical Manufacturing: For the production of high-value specialty chemicals requiring specific stereochemistry.
• Academic & Industrial Research: As a tool for developing new catalytic methodologies and exploring novel reaction pathways.
• Material Science: Potential applications in the development of chiral polymers or advanced functional materials.

Basic Information

Product Name	Phospholane, 1-[2-[(2R,5R)-2,5-Diethyl-1-Oxido-1-Phospholanyl]Phenyl]-2,5-Diethyl-, (2R,5R)-Rel-
CAS No.	2635339-89-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	rel-(2R,5R)-1-[2-[(2R,5R)-2,5-Diethyl-1-oxido-1-phospholanyl]phenyl]-2,5-diethylphospholane 1-oxide; (R,R)-DIPAMP derivative; Chiral bisphospholane ligand; 1,1'-Bis(diethylphospholanyl)benzene dioxide; Asymmetric phosphine oxide ligand; DuPhos-type ligand analog; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized to confirm identity, stereochemical purity, and chemical purity, typically via NMR, HPLC, and chiral analysis. Certificates of Analysis (COA) detailing specific results are available upon request. We adhere to a cGMP-compliant quality management system suitable for supporting pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.