Description

1H-Indole, 1-Ethyl-7-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)- is a high-value, functionalized indole derivative containing a pinacol boronate ester group, serving as a critical synthetic intermediate. This compound matters for its role in enabling efficient cross-coupling reactions, specifically Suzuki-Miyaura couplings, which are foundational to modern pharmaceutical and advanced materials research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and organic electronics industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in creating biaryl and heterobiaryl structures common in active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that require specific indole-based scaffolds.
• Material Science: Serves as a precursor for organic semiconductors, OLED (Organic Light-Emitting Diode) materials, and conductive polymers.
• Chemical Biology & Proteomics: Employed as a molecular probe or tag in bioconjugation and labeling strategies due to its reactive boronate handle.
• Academic & Contract Research: Essential reagent for methodological development in synthetic organic chemistry and catalysis studies.
• Scale-up & Process Chemistry: Used in pilot plants and kilo-labs for the optimization and production of target molecules at larger scales.

Basic Information

Product Name	1H-Indole, 1-Ethyl-7-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-
CAS No.	2621938-66-5
Molecular Formula	C₁₈H₂₆BNO₂
Molecular Weight	299.22 g/mol
Synonyms	1-Ethyl-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole; 7-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-ethyl-1H-indole; 1-Ethyl-1H-indole-7-boronic acid pinacol ester; 1-Ethyl-7-boronoindole pinacol ester; 1-Ethyl-7-(pinacolboryl)-1H-indole; 7-Borono-1-ethylindole pinacol ester; 1-Ethyl-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)indole
EINECS	Contact for details

Quality Control

Our 1H-Indole, 1-Ethyl-7-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure compliance with exacting R&D and process chemistry standards. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Typical 97-99%)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.