Description

4-Isoquinolinecarboxylic Acid, 7-(Trifluoromethyl)- is a high-value trifluoromethyl-substituted isoquinoline derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its core value lies in enabling the precise introduction of the trifluoromethyl group, a key pharmacophore known to enhance metabolic stability, lipophilicity, and bioavailability in active molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing potential drug candidates, especially in oncology, CNS, and anti-infective research where the CF3 group is crucial.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging the properties of the trifluoromethyl group.
• Material Science Research: Serves as a precursor for creating specialized ligands, catalysts, or organic electronic materials.
• Chemical Biology Probes: Utilized in the design of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke synthesis projects and library production.

Basic Information

Product Name	4-Isoquinolinecarboxylic Acid, 7-(Trifluoromethyl)-
CAS No.	2566174-18-1
Molecular Formula	C11H6F3NO2
Molecular Weight	241.17 g/mol
Synonyms	7-(Trifluoromethyl)isoquinoline-4-carboxylic acid; 7-Trifluoromethyl-4-isoquinolinecarboxylic Acid; 4-Carboxy-7-trifluoromethylisoquinoline; 7-Trifluoromethylisoquinoline-4-carboxylic Acid; 7-CF3-Isoquinoline-4-carboxylic Acid
EINECS	Contact for details

Quality Control

Every batch of 4-Isoquinolinecarboxylic Acid, 7-(Trifluoromethyl)- is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and MS is supplied with each shipment to guarantee reproducible results and supply chain reliability for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.