Description

4-Isoquinolinol, 7-(Trifluoromethyl)- is a specialized heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the unique combination of the isoquinoline scaffold and a strategically positioned trifluoromethyl group, which is highly sought after for modulating the physicochemical properties of target molecules. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it serves as a key precursor for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing potential drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, oncology, and anti-infective agents.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the trifluoromethyl group can enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the synthesis of advanced organic electronic materials, such as ligands for OLEDs or conductive polymers.
• Chemical Biology Probe: Utilized in the design and synthesis of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Catalyst Ligand Synthesis: Acts as a starting material for creating novel, complex ligands used in asymmetric catalysis and transition metal complexes.
• Custom Synthesis & Contract Manufacturing: A valuable substrate for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the fine chemical industry.

Basic Information

Product Name	4-Isoquinolinol, 7-(Trifluoromethyl)-
CAS No.	2566172-43-6
Molecular Formula	C10H6F3NO
Molecular Weight	213.16 g/mol
Synonyms	7-(Trifluoromethyl)isoquinolin-4-ol; 7-(Trifluoromethyl)-4-hydroxyisoquinoline; 4-Hydroxy-7-(trifluoromethyl)isoquinoline; 7-Trifluoromethyl-4-isoquinolinol; 4-Isoquinolinol, 7-(trifluoromethyl)-; 7-Trifluoromethylisoquinolin-4-ol; TFMIQ; 7-CF3-Isoquinolin-4-ol
EINECS	Contact for details

Quality Control

Every batch of 4-Isoquinolinol, 7-(Trifluoromethyl)- is produced and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment to guarantee it meets your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. The product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.