Description

Benzenemethanol, 5-Bromo-2,3-Difluoro-4-Methyl- is a high-purity, multi-functional halogenated benzyl alcohol derivative designed for advanced synthetic chemistry. This compound serves as a critical building block for pharmaceutical and agrochemical research, enabling the introduction of a bromo-difluoro-methyl substituted benzyl moiety into complex molecules. It is essential for researchers and process chemists in the life sciences sector who require precise and reliable intermediates for drug discovery and material science applications.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides, leveraging the bioactivity of the bromo and difluoro substituents.
• Liquid Crystal & OLED Materials: Serves as a fluorinated building block for electronic chemicals used in display and lighting technologies.
• Organic Ligand Preparation: Employed in the synthesis of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Cross-Coupling Reactions: The bromine atom makes it a suitable substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Fluorine Chemistry Research: A valuable compound for studying the effects of strategic fluorine substitution on molecular properties like lipophilicity and metabolic stability.

Basic Information

Product Name	Benzenemethanol, 5-Bromo-2,3-Difluoro-4-Methyl-
CAS No.	2484889-29-2
Molecular Formula	C8H7BrF2O
Molecular Weight	237.04 g/mol
Synonyms	5-Bromo-2,3-difluoro-4-methylbenzyl alcohol; (5-Bromo-2,3-difluoro-4-methylphenyl)methanol; 4-Methyl-5-bromo-2,3-difluorobenzyl alcohol; 2,3-Difluoro-5-bromo-4-methylbenzenemethanol; Benzenemethanol, 5-bromo-2,3-difluoro-4-methyl-; 5-Bromo-2,3-difluoro-p-tolylmethanol
EINECS	Contact for details

Quality Control

Our Benzenemethanol, 5-Bromo-2,3-Difluoro-4-Methyl- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring a reliable supply for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.