Description

Dl-2-Aminoadipic Acid (2,5,5-D3, 98%) is a deuterium-labeled analog of the endogenous metabolite 2-aminoadipic acid, a key intermediate in the lysine degradation pathway. This high-purity, isotopically enriched compound is essential for advanced research requiring precise metabolic tracing and quantification. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and contract research organizations (CROs) specializing in metabolomics, biomarker discovery, and the development of stable isotope dilution assays.

Application

• Internal Standard for LC-MS/MS Analysis: Serves as a critical quantitative reference standard in mass spectrometry for accurately measuring endogenous 2-aminoadipic acid levels in biological samples.
• Metabolic Pathway Tracing: Used in deuterium-labeling studies to elucidate the flux through the lysine degradation and saccharopine pathways in various disease models.
• Biomarker Research: Enables precise investigation into the role of 2-aminoadipic acid as a potential biomarker for conditions like diabetes, cardiovascular disease, and mitochondrial disorders.
• Drug Metabolism & Pharmacokinetics (DMPK): Employed in the development and validation of bioanalytical methods for novel therapeutics targeting related metabolic enzymes.
• Synthesis of Labeled Compounds: Acts as a deuterated building block for the synthesis of more complex isotopically labeled molecules for research and diagnostic purposes.

Basic Information

Product Name	Dl-2-Aminoadipic Acid (2,5,5-D3, 98%)
CAS No.	2483832-01-3
Molecular Formula	C₆H₈D₃NO₄
Molecular Weight	166.16 g/mol (for deuterated form)
Synonyms	DL-2-Aminoadipic-2,5,5-d3 Acid; (±)-2-Aminohexanedioic-2,5,5-d3 Acid; 2-Aminoadipic Acid-d3; α-Aminoadipic Acid-d3; DL-α-Aminoadipic Acid-d3; 2-Amino-1,6-hexanedioic Acid-d3; Aminoadipate-d3; Hexanedioic acid, 2-amino-, (DL)-, labeled with deuterium
EINECS	Contact for details

Quality Control

Every batch of our Dl-2-Aminoadipic Acid (2,5,5-D3, 98%) is produced and analyzed under strict quality management protocols. We guarantee high chemical and isotopic purity, with comprehensive characterization by NMR, MS, and HPLC. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity (≥98%), deuterium enrichment, and absence of critical impurities. Our quality system supports research requiring reliable and traceable reference materials.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation and storage under inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-enrichment)	≥ 98 atom % D (2,5,5-D3)
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.