Description

(R)-1-(3,4-Dimethoxybenzyl)-6,7-Dimethoxy-2,2-Dimethyl-1,2,3,4-Tetrahydroisoquinolin-2-Ium is a high-purity, advanced pharmaceutical intermediate with a defined stereochemistry. This compound is critical for the research and development of novel therapeutic agents, particularly in the field of central nervous system (CNS) and cardiovascular drug discovery. It is primarily sought after by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the synthesis of complex, biologically active molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel isoquinoline-based drug candidates.
• Neurological Research: Used in the development of potential therapeutics targeting neurological disorders and CNS pathways.
• Cardiovascular Drug Development: Serves as a precursor for compounds being investigated for cardiovascular applications.
• Asymmetric Synthesis: Valuable chiral synthon for constructing complex molecules with high enantiomeric purity.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization programs.
• Reference Standard: Used as a high-purity analytical standard for quality control and method development.

Basic Information

Item	Details
Product Name	(R)-1-(3,4-Dimethoxybenzyl)-6,7-Dimethoxy-2,2-Dimethyl-1,2,3,4-Tetrahydroisoquinolin-2-Ium
CAS No.	2480467-84-1
Molecular Formula	C23H31NO4+
Molecular Weight	385.50 g/mol
Synonyms	(R)-1-(3,4-Dimethoxybenzyl)-6,7-dimethoxy-2,2-dimethyl-1,2,3,4-tetrahydroisoquinolin-2-ium; (R)-1-(3,4-Dimethoxybenzyl)-6,7-dimethoxy-2,2-dimethyl-1,2,3,4-tetrahydroisoquinolinium; (R)-1-(3,4-Dimethoxybenzyl)-6,7-dimethoxy-2,2-dimethyl-1,2,3,4-tetrahydroisoquinoline-2-ium; (R)-1-(3,4-Dimethoxybenzyl)-6,7-dimethoxy-2,2-dimethyl-1,2,3,4-tetrahydroisoquinolin-2-ylium; (R)-1-(3,4-Dimethoxybenzyl)-6,7-dimethoxy-2,2-dimethyl-3,4-dihydroisoquinolin-2-ium; (R)-1-(Veratryl)-6,7-dimethoxy-2,2-dimethyl-1,2,3,4-tetrahydroisoquinolin-2-ium; (R)-1-(3,4-Dimethoxybenzyl)-6,7-dimethoxy-2,2-dimethyl-1,2,3,4-tetrahydroisoquinolin-2-Ium chloride (salt form may vary).
EINECS	Contact for details

Quality Control

Our (R)-1-(3,4-Dimethoxybenzyl)-6,7-Dimethoxy-2,2-Dimethyl-1,2,3,4-Tetrahydroisoquinolin-2-Ium is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.