Description

1,3-Benzoxaphosphole, 4-[2,6-Bis(1-Methylethoxy)Phenyl]-3-(1,1-Dimethylethyl)-2,3-Dihydro-, (3S)- is a high-purity, chiral organophosphorus compound of significant interest in advanced chemical synthesis. Its value lies in its unique structure, which serves as a sophisticated ligand or building block for creating novel catalysts and functional materials. This product is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries, particularly those focused on asymmetric synthesis and the development of new catalytic systems.

Application

• Asymmetric Catalysis: As a chiral ligand or precursor for transition metal catalysts used in enantioselective synthesis.
• Pharmaceutical Intermediates: A key building block in the research and development of active pharmaceutical ingredients (APIs) requiring specific stereochemistry.
• Agrochemical Research: Used in the synthesis of novel, biologically active compounds for crop protection.
• Material Science: A precursor for the development of advanced polymers or functional materials with specific electronic or optical properties.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic and organometallic chemistry.
• Process Chemistry Development: Evaluation as a ligand for scaling up enantioselective transformations in pilot and commercial manufacturing.

Basic Information

Product Name	1,3-Benzoxaphosphole, 4-[2,6-Bis(1-Methylethoxy)Phenyl]-3-(1,1-Dimethylethyl)-2,3-Dihydro-, (3S)-
CAS No.	2448341-44-2
Molecular Formula	C24H31O3P
Molecular Weight	398.48 g/mol
Synonyms	(3S)-4-[2,6-Bis(propan-2-yloxy)phenyl]-3-(tert-butyl)-2,3-dihydro-1,3-benzoxaphosphole; (3S)-3-tert-Butyl-4-[2,6-di(propan-2-yloxy)phenyl]-2,3-dihydro-1,3-benzoxaphosphole; (S)-3-(tert-Butyl)-4-(2,6-diisopropoxyphenyl)-2,3-dihydrobenzo[d][1,3]oxaphosphole; Chiral Dihydrobenzoxaphosphole Ligand; Chiral Phosphorus Heterocycle; Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our 1,3-Benzoxaphosphole derivative is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure high chemical and enantiomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.