Description

1H-Indole, 5-Methyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)- is a high-purity, advanced pharmaceutical intermediate and versatile building block for organic synthesis. This compound is valued for its role as a key precursor in the development of complex molecules, particularly in medicinal chemistry. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for applications in drug discovery and fine chemical production.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially for compounds targeting central nervous system (CNS) disorders.
• Suzuki-Miyaura Cross-Coupling Reactions: The boronic ester pinacol group makes it an essential reagent for palladium-catalyzed cross-coupling, enabling the formation of carbon-carbon bonds to construct complex indole derivatives.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that leverage the indole scaffold for enhanced biological activity.
• Material Science & Organic Electronics: Serves as a precursor for creating functional organic materials, such as organic light-emitting diodes (OLEDs) and conductive polymers.
• Academic & R&D Laboratories: Employed in methodological studies and the discovery of new synthetic pathways in organic chemistry.
• Ligand Synthesis: Can be utilized to develop novel ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	1H-Indole, 5-Methyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-
CAS No.	2448157-13-7
Molecular Formula	C15H20BNO2
Molecular Weight	257.14 g/mol
Synonyms	5-Methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-5-methyl-1H-indole; 5-Methyl-1H-indole-3-boronic acid pinacol ester; 5-Methylindole-3-boronic acid pinacol ester; 3-Borono-5-methyl-1H-indole pinacol ester; 5-Methyl-3-indolylboronic acid pinacol ester; 5-Methyl-1H-indol-3-ylboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 1H-Indole, 5-Methyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.