Description

2-(2-Bromo-4-Oxo-4H-Cyclopenta[B]Thiophen-6(5H)-Ylidene)Malononitrile is a high-value, specialized organic intermediate featuring a fused cyclopentathiophene core functionalized with bromo, oxo, and malononitrile groups. This unique molecular architecture makes it a critical building block for the synthesis of advanced functional materials and active pharmaceutical ingredients (APIs). It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and organic electronics industries for constructing complex heterocyclic systems.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition or acting as protease inhibitors.
• Agrochemical Research: Used in developing new generations of herbicides, fungicides, and insecticides due to its reactive bromine and electron-accepting malononitrile moiety.
• Organic Semiconductor Development: Acts as an electron-deficient unit (acceptor) in the design of donor-acceptor (D-A) type polymers and small molecules for organic photovoltaics (OPVs) and field-effect transistors (OFETs).
• Dye and Pigment Synthesis: Employed in creating specialized dyes and pigments, where the thiophene and malononitrile groups contribute to color and light-absorption properties.
• Material Science Research: Utilized as a building block for metal-organic frameworks (MOFs) or covalent organic frameworks (COFs) with tailored electronic properties.
• Academic & Contract Research: A valuable reagent for methodological studies in organic synthesis, including cross-coupling reactions and cycloadditions.

Basic Information

Product Name	2-(2-Bromo-4-Oxo-4H-Cyclopenta[B]Thiophen-6(5H)-Ylidene)Malononitrile
CAS No.	2446466-88-0
Molecular Formula	C10H3BrN2OS
Molecular Weight	279.11 g/mol
Synonyms	2-(2-Bromo-4-oxo-4H-cyclopenta[b]thiophen-6(5H)-ylidene)malononitrile; 2-Bromo-6-(dicyanomethylene)-4,5,6,7-tetrahydro-4-oxocyclopenta[b]thiophene; 6-(Dicyanomethylene)-2-bromo-4,5,6,7-tetrahydro-4-oxocyclopenta[b]thiophene; 2-Bromo-4-oxo-4H-cyclopenta[b]thiophene-6(5H)-ylidenemalononitrile; Bromocyclopentathiophene malononitrile derivative
EINECS	Contact for details

Quality Control

Every batch of 2-(2-Bromo-4-Oxo-4H-Cyclopenta[B]Thiophen-6(5H)-Ylidene)Malononitrile is manufactured and tested under a strict quality management system. We provide comprehensive analytical data including HPLC purity, NMR (1H & 13C), and mass spectrometry to verify identity and quality. Certificates of Analysis (COA) detailing all specifications are available upon request and can be tailored to meet specific project or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should be conducted under subdued light or amber containers to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.