Description

1H-Indole-6-Carboxamide, 7-Bromo- is a high-purity, advanced pharmaceutical intermediate with a distinct brominated indole scaffold. This compound is valued for its role as a critical building block in modern medicinal chemistry, enabling the synthesis of novel therapeutic agents. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of targeted small-molecule drugs, particularly in oncology and CNS research.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates targeting specific biological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic entities.
• Proteolysis-Targeting Chimera (PROTAC) Development: Acts as a potential ligand or linker component in the design of targeted protein degraders.
• Kinase Inhibitor Synthesis: Utilized in the construction of brominated heterocyclic cores for potential kinase inhibitor libraries.
• Chemical Biology Probes: Employed in the development of tool compounds for studying enzyme function and cellular processes.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting drug discovery and development pipelines.

Basic Information

Product Name	1H-Indole-6-Carboxamide, 7-Bromo-
CAS No.	2417302-02-2
Molecular Formula	C9H7BrN2O
Molecular Weight	239.07 g/mol
Synonyms	7-Bromo-1H-indole-6-carboxamide; 7-Bromoindole-6-carboxamide; 1H-Indole-6-carboxamide, 7-bromo-; 2417302-02-2; 7-Bromo-6-carbamoylindole; 6-Carbamoyl-7-bromoindole; 7-Bromo-1H-indole-6-carboxylic acid amide
EINECS	Contact for details

Quality Control

Our 1H-Indole-6-Carboxamide, 7-Bromo- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.