Description

Isoquinoline, 6-Bromo-1-Chloro-8-Fluoro- is a high-purity, multi-halogenated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its precise molecular architecture, which enables the targeted introduction of halogen atoms to modulate the electronic and steric properties of complex molecules. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors, antimicrobials, and central nervous system (CNS) agents.
• Agrochemical Research: Used to construct complex heterocyclic scaffolds for the development of new-generation herbicides, fungicides, and pesticides with enhanced efficacy.
• Material Science: Serves as a building block for creating functional organic materials, such as organic light-emitting diodes (OLEDs) and conductive polymers, where halogen atoms fine-tune electronic properties.
• Chemical Biology & Probe Development: Employed in the design and synthesis of molecular probes and tags for studying biological processes and target engagement.
• Academic & Contract Research: Essential for methodological development and exploration of new chemical spaces in university laboratories and contract research organizations (CROs).
• Custom Synthesis & Scale-Up: A critical starting material for custom synthesis projects, supporting process research and development from milligram to kilogram scale.

Basic Information

Item	Detail
Product Name	Isoquinoline, 6-Bromo-1-Chloro-8-Fluoro-
CAS No.	2411635-02-2
Molecular Formula	C9H4BrClFN
Molecular Weight	260.49 g/mol
Synonyms	6-Bromo-1-chloro-8-fluoroisoquinoline; 1-Chloro-6-bromo-8-fluoroisoquinoline; 8-Fluoro-6-bromo-1-chloroisoquinoline; 6-Bromo-8-fluoro-1-chloroisoquinoline; Isoquinoline, 1-chloro-6-bromo-8-fluoro-; (6-Bromo-8-fluoro-1-isoquinolinyl)chloride (non-standard); BCFI (abbreviation)
EINECS	Contact for details

Quality Control

Our Isoquinoline, 6-Bromo-1-Chloro-8-Fluoro- is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our commitment to cGMP principles and ISO-aligned processes guarantees a reliable supply of high-purity material for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.