Description

Fmoc-β-Ala-Gln(Trt)-OH is a protected tripeptide building block widely used in solid-phase peptide synthesis (SPPS). This compound is critical for researchers and manufacturers requiring high-purity intermediates to construct complex peptide sequences with precise control. It is essential for pharmaceutical R&D, particularly in the development of therapeutic peptides, diagnostic agents, and biochemical tools for proteomics.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key Fmoc-protected amino acid derivative for the sequential assembly of custom peptide chains.
• Pharmaceutical Intermediate: For the research and production of active pharmaceutical ingredients (APIs) in peptide-based therapeutics.
• Bioconjugation & Probe Development: Used to introduce specific functional handles or labeled amino acids into peptides for diagnostic and imaging applications.
• Chemical Biology Research: A vital reagent for studying protein-protein interactions, enzyme substrates, and signal transduction pathways.
• Antibody-Drug Conjugate (ADC) Payload Synthesis: Serves as a component in constructing peptide linkers or cytotoxic peptide payloads for targeted cancer therapies.
• Peptide Library Construction: Enables the generation of diverse peptide libraries for high-throughput screening in drug discovery.

Basic Information

Product Name	Fmoc-β-Ala-Gln(Trt)-OH
CAS No.	2411591-25-6
Molecular Formula	C43H41N3O6
Molecular Weight	695.81 g/mol
Synonyms	Fmoc-β-Ala-Gln(Trt)-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-aminopropanoyl-N2-[(triphenylmethyl)-L-glutamine; Fmoc-β-alanyl-N2-(trityl)-L-glutamine; Fmoc-3-aminopropanoyl-Gln(Trt)-OH; Nα-Fmoc-Nγ-trityl-β-alanyl-glutamine; Fmoc-β-Ala-Gln(Trt)-OH; Protected Tripeptide Building Block Fmoc-β-Ala-Gln(Trt)
EINECS	Contact for details

Quality Control

Our Fmoc-β-Ala-Gln(Trt)-OH is manufactured under strict quality systems to ensure batch-to-batch consistency for critical research and cGMP applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to stringent in-house specifications aligned with industry best practices for peptide synthesis building blocks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the sealed container to reach ambient temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.