Description

2-[[(3α,5β,7α)-3,7-Dihydroxy-24-Oxocholan-24-Yl-2,2,4,4-D4]Amino]-Ethanesulfonicacid,Monosodiumsalt is a deuterated derivative of a bile acid analogue, specifically designed for advanced research and development applications. This compound is critical for studies requiring stable isotope labeling, such as metabolic pathway tracing and pharmacokinetic analysis. It is primarily utilized by pharmaceutical R&D teams, analytical laboratories, and academic institutions focused on hepatobiliary and metabolic research.

Application

• As a stable isotope-labeled internal standard for the precise quantification of bile acids and their metabolites in biological matrices via LC-MS/MS.
• In pharmaceutical research for investigating the metabolism, distribution, and excretion of novel therapeutic agents targeting liver and metabolic diseases.
• For mechanistic studies of bile acid transporters (e.g., ASBT, NTCP) and nuclear receptors (e.g., FXR, TGR5) using deuterium-labeled probes.
• In the development and validation of highly sensitive diagnostic assays for cholestatic and metabolic disorders.
• As a key research-grade biochemical in academic settings for exploring lipid metabolism and signaling pathways.
• For quality control and method development in analytical chemistry laboratories specializing in steroid and lipid analysis.

Basic Information

Product Name	2-[[(3α,5β,7α)-3,7-Dihydroxy-24-Oxocholan-24-Yl-2,2,4,4-D4]Amino]-Ethanesulfonicacid,Monosodiumsalt
CAS No.	2410279-85-3
Molecular Formula	C₂₆H₄₀D₄NNaO₇S
Molecular Weight	Contact for details
Synonyms	Monosodium 2-[[(3α,5β,7α)-3,7-Dihydroxy-24-oxocholan-24-yl-2,2,4,4-D4]amino]ethanesulfonate; Deuterated Tauro-3α,7α-dihydroxy-5β-cholan-24-oic Acid Sodium Salt (d4); Sodium 2-[(3α,7α-Dihydroxy-24-oxo-5β-cholan-24-yl-D4)amino]ethanesulfonate; Taurodeoxycholic Acid-d4 Sodium Salt (3α,7α-dihydroxy isomer); TCA-d4 Sodium Salt; d4-Taurochenodeoxycholate Sodium; Deuterated Bile Acid Salt; 2-Aminoethanesulfonic Acid Derivative of Deuterated Cholic Acid
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques, including NMR and mass spectrometry, to confirm isotopic enrichment and chemical purity. Certificates of Analysis (COA) detailing purity, isotopic purity (D-enrichment), and impurity profiles are available upon request. We adhere to a cGMP-compliant quality management system suitable for research and non-GMP pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC-MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Water Content (KF)	≤ 5.0 %
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.