Description

2,6-Diphenyl-4-(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Pyridine is a high-value, advanced pharmaceutical intermediate and building block featuring a pinacol boronate ester functional group. This compound matters for its critical role in enabling Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern organic synthesis for creating complex carbon-carbon bonds. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for the synthesis of novel active ingredients and functional molecules. The CAS number for this product is 2408429-06-9.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Suzuki-Miyaura Cross-Coupling Reagent: Enables the efficient formation of biaryl and heterobiaryl structures, which are prevalent scaffolds in medicinal chemistry and material science.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring complex aryl-aryl linkages.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a precursor for electron-transport materials and host molecules in display and lighting technologies.
• Ligand and Catalyst Development: Acts as a starting material for creating novel bidentate or tridentate ligands used in homogeneous catalysis.
• Polymer and Material Science: Incorporated into monomers for the production of advanced polymers with specific electronic or optical properties.
• Academic and Contract Research: Essential reagent for methodology development and synthetic chemistry research in academic and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	2,6-Diphenyl-4-(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Pyridine
CAS No.	2408429-06-9
Molecular Formula	C29H28BNO2
Molecular Weight	433.35 g/mol
Synonyms	4-[3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-2,6-diphenylpyridine; 2,6-Diphenyl-4-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]pyridine; 3-(2,6-Diphenylpyridin-4-yl)phenylboronic acid pinacol ester; 2,6-Diphenyl-4-(3-boronophenyl)pyridine pinacol ester; Boronic acid, B-[3-(2,6-diphenyl-4-pyridinyl)phenyl]-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 2,6-Diphenyl-4-(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistent performance in cross-coupling applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 3.0%; Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.