Description

2-Morpholino-3-(trifluoromethyl)pyridine-5-boronic acid is a high-value, multifunctional boronic acid derivative designed for advanced synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly those targeting CNS disorders and oncology.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science: Employed in the synthesis of organic electronic materials, such as ligands for OLEDs and charge-transport molecules.
• Chemical Biology: Acts as a versatile handle for bioconjugation and the development of chemical probes and PROTACs (Proteolysis Targeting Chimeras).
• Catalyst & Ligand Development: Serves as a starting material for creating novel bidentate ligands used in homogeneous catalysis.
• Custom Synthesis & Contract Manufacturing: An essential reagent for CROs and CDMOs engaged in custom synthesis projects requiring specific pyridine-morpholine scaffolds.

Basic Information

Item	Detail
Product Name	2-Morpholino-3-(Trifluoromethyl)Pyridine-5-Boronic Acid
CAS No.	2377606-45-4
Molecular Formula	C10H12BF3N2O3
Molecular Weight	276.03 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-morpholino-3-(trifluoromethyl)pyridine; 2-Morpholin-4-yl-3-(trifluoromethyl)pyridine-5-boronic acid; 3-Trifluoromethyl-2-morpholinopyridine-5-boronic acid; 2-Morpholino-3-trifluoromethyl-5-pyridineboronic acid; [2-Morpholino-3-(trifluoromethyl)pyridin-5-yl]boronic acid; 2377606-45-4; 2-Morpholino-3-(trifluoromethyl)-5-pyridineboronic acid
EINECS	Contact for details

Quality Control

Our 2-Morpholino-3-(trifluoromethyl)pyridine-5-boronic acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.