Description

3,6,9,12,15,18,21,24-Octaoxahexacosane, 1,26-Dibromo- is a high-purity, symmetrical polyethylene glycol (PEG) derivative featuring terminal bromine atoms, making it a versatile and valuable bifunctional linker in advanced chemical synthesis. This compound is engineered to provide reliable reactivity for nucleophilic substitution and polymerization reactions, ensuring consistent performance in demanding applications. It is a critical intermediate for researchers and manufacturers in the pharmaceutical, polymer science, and materials chemistry sectors who require precise control over molecular architecture and surface functionalization.

Application

• Pharmaceutical Intermediate: Used as a key building block for the synthesis of prodrugs, antibody-drug conjugates (ADCs), and PEGylated therapeutic agents to enhance solubility and bioavailability.
• Polymer & Material Science: Serves as a bifunctional initiator or cross-linking agent for the synthesis of block copolymers, hydrogels, and functionalized nanomaterials.
• Surface Modification: Employed to create self-assembled monolayers (SAMs) or to graft functional polymer brushes onto surfaces for biomedical devices and sensors.
• Dendrimer & Macromolecule Synthesis: Acts as a core or spacer unit in the convergent or divergent synthesis of complex dendritic structures and star polymers.
• Ligand & Catalyst Attachment: Facilitates the immobilization of catalysts, ligands, or biomolecules onto solid supports for catalysis and separation technologies.
• Click Chemistry: An ideal precursor for further functionalization via azide-alkyne cycloaddition or other bioorthogonal reactions to create tailored macromolecules.

Basic Information

Product Name	3,6,9,12,15,18,21,24-Octaoxahexacosane, 1,26-Dibromo-
CAS No.	2376383-09-2
Molecular Formula	C18H36Br2O8
Molecular Weight	548.28 g/mol
Synonyms	1,26-Dibromo-3,6,9,12,15,18,21,24-octaoxahexacosane; α,ω-Dibromo-poly(ethylene glycol) (PEG-Br2); Br-PEG8-Br; Poly(ethylene glycol) bis(2-bromoethyl) ether (n~8); PEG 400 dibromide (approx.); 2,2'-(Ethane-1,2-diylbis(oxy))bis(ethane-2,1-diyl) bis(2-bromoacetate) (linear form); Bis(2-bromoethyl) octaethylene glycol ether; Dibromooctaethylene glycol
EINECS	Contact for details

Quality Control

Our 3,6,9,12,15,18,21,24-Octaoxahexacosane, 1,26-Dibromo- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and titration methods, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (NMR)	Conforms
Water Content (KF)	≤ 0.5%
Bromine Content	28.0 - 30.0 %
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.