Description

Cyproterone Acetate-D3 is a deuterium-labeled analog of the steroidal antiandrogen Cyproterone Acetate, specifically designed for use as an internal standard in quantitative bioanalytical methods. This high-purity stable isotope-labeled compound is essential for ensuring the accuracy and reliability of mass spectrometry-based analyses, particularly in pharmacokinetic and metabolism studies. It is a critical tool for pharmaceutical R&D laboratories, clinical research organizations, and regulatory testing facilities focused on endocrinology and oncology drug development.

Application

• Primary use as an internal standard in Liquid Chromatography-Mass Spectrometry (LC-MS/MS) for the quantification of Cyproterone Acetate in biological matrices.
• Enabling precise pharmacokinetic (PK) and bioequivalence studies for generic and novel drug formulations containing Cyproterone Acetate.
• Facilitating drug metabolism and disposition (DMPK) research to understand the compound's metabolic pathways.
• Supporting clinical trial analysis by providing a reliable reference for measuring drug concentrations in patient plasma or serum samples.
• Use in forensic and anti-doping analysis for the accurate detection and confirmation of the parent compound.
• Application in environmental and food safety testing for trace-level detection methods requiring high specificity.

Basic Information

Product Name	Cyproterone Acetate-D3
CAS No.	2376035-90-2
Molecular Formula	C₂₄H₂₆D₃ClO₄
Molecular Weight	~428.0 g/mol
Synonyms	6-Chloro-1β,2β-dihydro-17α-hydroxy-3'H-cyclopropa[1,2]pregna-1,4,6-triene-3,20-dione Acetate-d3; 1,2α-Methylene-6-chloro-17α-hydroxy-4,6-pregnadiene-3,20-dione 17α-Acetate-d3; Androcur-d3; SH-714-d3; CPA-d3; Cyproterone-d3 Acetate; 1,2α-Methylene-6-chloro-δ⁶-17α-acetoxyprogesterone-d3
EINECS	Contact for details

Quality Control

Every batch of Cyproterone Acetate-D3 is manufactured and tested under strict quality management systems. We guarantee high chemical and isotopic purity, with comprehensive characterization using NMR, HPLC, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, isotopic enrichment, and solvent residue levels to ensure suitability for sensitive analytical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label. This material is hygroscopic (moisture-sensitive) and should be kept in a dry environment. For long-term storage, consider desiccant in the container.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D3)	≥ 99.0 atom % D
Chemical Purity	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.