Description

Methyl 4-Formylbicyclo[2.1.1]Hexane-1-Carboxylate CAS NO 2375195-62-1 is a high-purity, advanced pharmaceutical intermediate featuring a unique strained bicyclic scaffold. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), enabling the exploration of new chemical space in drug discovery. It is primarily sought by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for developing treatments targeting the central nervous system and metabolic diseases.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, especially in neurology and metabolic disorder pipelines.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing complex, three-dimensional molecular architectures to improve drug-like properties such as solubility and metabolic stability.
• Agrochemical Synthesis: Serves as a precursor for developing novel crop protection agents with unique modes of action.
• Material Science: Potential monomer or cross-linking agent for creating specialty polymers with tailored thermal and mechanical properties.
• Academic Research: Employed in organic synthesis studies to investigate novel reaction pathways and strain-release chemistry.

Basic Information

Product Name	Methyl 4-Formylbicyclo[2.1.1]Hexane-1-Carboxylate
CAS No.	2375195-62-1
Molecular Formula	C10H12O3
Molecular Weight	180.20 g/mol
Synonyms	Methyl 4-formylbicyclo[2.1.1]hexane-1-carboxylate; 1-(Methoxycarbonyl)bicyclo[2.1.1]hexane-4-carboxaldehyde; Bicyclo[2.1.1]hexane-1-carboxylic acid, 4-formyl-, methyl ester; Methyl bicyclo[2.1.1]hexane-1-carboxylate-4-carboxaldehyde
EINECS	Contact for details

Quality Control

Our Methyl 4-Formylbicyclo[2.1.1]Hexane-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your R&D and cGMP-compliant workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity, the material should be stored under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.