Description

(S)-1-(Thiazol-2-Yl)Ethanamine Hydrochloride is a high-purity chiral amine building block essential for advanced pharmaceutical research and development. This compound serves as a critical intermediate in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for targeted therapies. It is primarily utilized by medicinal chemists and process development scientists within the pharmaceutical, biotechnology, and fine chemical industries to create new drug candidates with specific stereochemical configurations.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug molecules, especially in oncology and central nervous system (CNS) therapeutic areas.
• Asymmetric Synthesis: Used as a building block in catalytic asymmetric reactions to construct complex molecules with high enantiomeric purity.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in stereoselective transformations.
• Agrochemical Research: Employed in the synthesis of advanced, enantiomerically pure crop protection agents and pesticides.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Process Chemistry: Investigated for scalable synthesis routes in the development of commercial manufacturing processes for APIs.

Basic Information

Product Name	(S)-1-(Thiazol-2-Yl)Ethanamine Hydrochloride
CAS No.	2323582-65-4
Molecular Formula	C5H9ClN2S
Molecular Weight	164.66 g/mol
Synonyms	(S)-1-(Thiazol-2-yl)ethan-1-amine hydrochloride; (S)-1-(1,3-Thiazol-2-yl)ethylamine hydrochloride; (S)-2-(1-Aminoethyl)thiazole hydrochloride; (S)-α-Methyl-2-thiazoleethanamine hydrochloride; (S)-Thiazol-2-ylethylamine hydrochloride; (S)-A-TEA HCl; (S)-1-(2-Thiazolyl)ethylamine hydrochloride
EINECS	Contact for details

Quality Control

Our (S)-1-(Thiazol-2-Yl)Ethanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.